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Microstructure and mechanical properties of in situ Streptococcus mutans biofilms.
- Source :
-
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2014 Jan 08; Vol. 6 (1), pp. 327-32. Date of Electronic Publication: 2013 Dec 26. - Publication Year :
- 2014
-
Abstract
- Insight into live microbial biofilm microstructure and mechanical properties and their interactions with the underlying substrate can lead to the development of new remedial strategies and/or materials. Here we report mechanical properties of dental pathogenic Streptococcus mutans biofilms, grown on a polystyrene-coated plate of a shear rheometer in physiologically relevant conditions, precisely controlled in a custom built bioreactor. In situ measurements demonstrated the importance of microstructure and composition of extracellular polymeric substances on the biofilm modulus. The biofilms behave like a weak gel with storage moduli higher than loss moduli. The simple but robust experimental technique presented here can easily be extended to other biofilm-material systems.
Details
- Language :
- English
- ISSN :
- 1944-8252
- Volume :
- 6
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- ACS applied materials & interfaces
- Publication Type :
- Academic Journal
- Accession number :
- 24351115
- Full Text :
- https://doi.org/10.1021/am404344h