Back to Search Start Over

[Occurrence and molecular pathology of low grade gliomas].

Authors :
Murnyák B
Csonka T
Klekner A
Hortobágyi T
Source :
Ideggyogyaszati szemle [Ideggyogy Sz] 2013 Sep 30; Vol. 66 (9-10), pp. 305-11.
Publication Year :
2013

Abstract

Background: The WHO grade I. and II. low-grade gliomas represent nearly the 15% of all primary brain tumors. These tumours contain clinically, histologically and molecularly distinct tumor types. According to their histologic characteristic, grade II glial tumours are the diffuse astrocytoma, oligodendroglioma and oligoastrocytoma subgroups; ependymal tumors are not included in this study.<br />Methods: In our publication, we analysed the histologically diagnosed glioma cases between 2007 and 2011 at our institution.<br />Results: Low-grade gliomas were diagnosed in 127 cases (62 male / 65 female), and the mean ages were 39 years (+/- 20.3). More than half of the cancers were localized in the frontal lobe, and the second most frequent area was the temporal lobe. Finally, we complete our report with an overview of major molecular pathways in low-grade gliomas.

Details

Language :
Hungarian
ISSN :
0019-1442
Volume :
66
Issue :
9-10
Database :
MEDLINE
Journal :
Ideggyogyaszati szemle
Publication Type :
Academic Journal
Accession number :
24358685