Back to Search
Start Over
Antibacterial chromene and chromane stilbenoids from Hymenocardia acida.
- Source :
-
Phytochemistry [Phytochemistry] 2014 Feb; Vol. 98, pp. 216-22. Date of Electronic Publication: 2013 Dec 19. - Publication Year :
- 2014
-
Abstract
- Six chromene stilbenoids and one chromane stilbenoid were isolated from the African tree Hymenocardia acida. Several were moderately active against methicillin-resistant Staphylococcus aureus clinical isolate MRSA-108, including hymenocardichromanic acid, which was active at 8 μg/ml. None had IC50 values <20 μM in antiproliferation assays against several human cancer cell lines.<br /> (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Subjects :
- Anti-Bacterial Agents chemistry
Anti-Bacterial Agents isolation & purification
Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic pharmacology
Benzopyrans chemistry
Benzopyrans isolation & purification
Cell Line, Tumor
Cell Proliferation drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Microbial Sensitivity Tests
Molecular Structure
Plant Leaves chemistry
Stilbenes chemistry
Stilbenes isolation & purification
Structure-Activity Relationship
Anti-Bacterial Agents pharmacology
Antineoplastic Agents, Phytogenic chemical synthesis
Benzopyrans pharmacology
Methicillin-Resistant Staphylococcus aureus drug effects
Phyllanthus chemistry
Stilbenes pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-3700
- Volume :
- 98
- Database :
- MEDLINE
- Journal :
- Phytochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 24361290
- Full Text :
- https://doi.org/10.1016/j.phytochem.2013.11.012