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[Ampicillin pharmacokinetics in prostatic adenoma patients].

Authors :
Iakovlev VP
Skala LZ
Slobodskoĭ RA
Nekhorosheva AG
Lur'e LA
Source :
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology [Antibiot Med Biotekhnol] 1987 Jul; Vol. 32 (7), pp. 525-8.
Publication Year :
1987

Abstract

Studies on ampicillin pharmacokinetics in patients with prostate adenoma showed that adenoma did not influence the antibiotic kinetics. The ampicillin maximum concentration in tissues and organs of the urinary corresponded to the peak concentrations in blood. Therefore, development of dosage regimens providing the drug efficient concentrations in tissues and organs of the urinary tract should be based on ampicillin kinetics in the blood.

Details

Language :
Russian
ISSN :
0233-7525
Volume :
32
Issue :
7
Database :
MEDLINE
Journal :
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology
Publication Type :
Academic Journal
Accession number :
2445279