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Tissue engineering is a promising method for the repair of spinal cord injuries (Review).

Authors :
Ji W
Hu S
Zhou J
Wang G
Wang K
Zhang Y
Source :
Experimental and therapeutic medicine [Exp Ther Med] 2014 Mar; Vol. 7 (3), pp. 523-528. Date of Electronic Publication: 2013 Dec 18.
Publication Year :
2014

Abstract

Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to build up synapses with the target cells are the focus of current research. Target cells are located in the damaged spinal cord which create a connect with the scaffold. As tissue engineering technology is developed for use in a variety of different areas, particularly the biomedical field, a clear understanding of the mechanisms of tissue engineering is important. This review establishes how this technology may be used in basic experiments with regard to SCI and considers its potential future clinical use.

Details

Language :
English
ISSN :
1792-0981
Volume :
7
Issue :
3
Database :
MEDLINE
Journal :
Experimental and therapeutic medicine
Publication Type :
Academic Journal
Accession number :
24520240
Full Text :
https://doi.org/10.3892/etm.2013.1454