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Adenylyl cyclases in the digestive system.
- Source :
-
Cellular signalling [Cell Signal] 2014 Jun; Vol. 26 (6), pp. 1173-81. Date of Electronic Publication: 2014 Feb 09. - Publication Year :
- 2014
-
Abstract
- Adenylyl cyclases (ACs) are a group of widely distributed enzymes whose functions are very diverse. There are nine known transmembrane AC isoforms activated by Gαs. Each has its own pattern of expression in the digestive system and differential regulation of function by Ca(2+) and other intracellular signals. In addition to the transmembrane isoforms, one AC is soluble and exhibits distinct regulation. In this review, the basic structure, regulation and physiological roles of ACs in the digestive system are discussed.<br /> (Copyright © 2014 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-3913
- Volume :
- 26
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Cellular signalling
- Publication Type :
- Academic Journal
- Accession number :
- 24521753
- Full Text :
- https://doi.org/10.1016/j.cellsig.2014.01.033