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Baroreflex activation therapy in patients with pre-existing implantable cardioverter-defibrillator: compatible, complementary therapies.

Authors :
Madershahian N
Scherner M
Müller-Ehmsen J
Halbach M
Hickethier T
Velden R
Choi YH
Wippermann J
Wahlers T
Source :
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2014 Jun; Vol. 16 (6), pp. 861-5. Date of Electronic Publication: 2014 Feb 13.
Publication Year :
2014

Abstract

Aims: The Neo™ System (CVRx) is an implantable device, CE certified for the treatment of resistant hypertension and investigationally used to treat systolic heart failure by electrical stimulation of the carotid baroreceptors. It is unknown whether interaction might exist between the Neo System and implantable cardioverter-defibrillators (ICDs).<br />Methods and Results: Compatibility of the Neo device was tested in seven consecutive patients with pre-existing ICDs. Intra- and post-operative testing was completed with ICD and Neo settings programmed to provoke interaction. Intracardiac electrograms were printed to determine interaction with the ICD. Interaction testing during implantation and follow-up showed that there was no device-device interaction. No interaction was observed at maximum atrial and ventricular sensitivity settings and maximum Neo output settings.<br />Conclusion: Combined therapy with the Neo device and at least in this study reported that transvenous ICD systems can be performed safely.<br /> (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.)

Details

Language :
English
ISSN :
1532-2092
Volume :
16
Issue :
6
Database :
MEDLINE
Journal :
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Publication Type :
Academic Journal
Accession number :
24525551
Full Text :
https://doi.org/10.1093/europace/eut403