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Strongyloides stercoralis genotypes in humans in Cambodia.
- Source :
-
Parasitology international [Parasitol Int] 2014 Jun; Vol. 63 (3), pp. 533-6. Date of Electronic Publication: 2014 Feb 14. - Publication Year :
- 2014
-
Abstract
- Little is known about the genetic variability of the soil-transmitted nematode, Strongyloides stercoralis, in humans. We sequenced portions of the small subunit rDNA (SSU), including the hyper variable regions (HVR) I and IV from S. stercoralis larvae derived from individuals living in a rural setting in Cambodia. We identified three polymorphic positions, including a previously reported one within the HVR I. HVR IV was invariable. Six different SSU alleles existed in our sample. Although different genotypes of S. stercoralis were found in the same individuals, no heterozygous larvae were found. This indicates that there is no or very little interbreeding between the different genotypes. Further studies are needed to examine if this is because sexual reproduction, which is facultative, is rare in our study area's S. stercoralis population or because what is considered to be S. stercoralis today is actually a complex of closely related species or subspecies.<br /> (Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Animals
Base Sequence
Cambodia epidemiology
DNA, Helminth genetics
DNA, Helminth metabolism
Female
Genotype
Humans
Larva
Molecular Sequence Data
RNA, Ribosomal, 18S genetics
RNA, Ribosomal, 18S metabolism
Strongyloides stercoralis classification
Strongyloides stercoralis isolation & purification
Strongyloidiasis epidemiology
Strongyloides stercoralis genetics
Strongyloidiasis parasitology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-0329
- Volume :
- 63
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Parasitology international
- Publication Type :
- Academic Journal
- Accession number :
- 24530857
- Full Text :
- https://doi.org/10.1016/j.parint.2014.01.010