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Detection of coccidioidal antibodies in serum of a small rodent community in Baja California, Mexico.
- Source :
-
Fungal biology [Fungal Biol] 2014 Mar; Vol. 118 (3), pp. 330-9. Date of Electronic Publication: 2014 Jan 31. - Publication Year :
- 2014
-
Abstract
- Coccidioidomycosis (Valley Fever) represents a serious threat to inhabitants of endemic areas of North America. Despite successful clinical isolations of the fungal etiological agent, Coccidioides spp., the screening of environmental samples has had low effectiveness, mainly because of the poor characterization of Coccidioides ecological niche. We explored Valle de las Palmas, Baja California, Mexico, a highly endemic area near the U.S.-Mexico border, where we previously detected Coccidioides via culture-independent molecular methods. By testing the serum from 40-trapped rodents with ELISA, we detected antibodies against Coccidioides in two species: Peromyscus maniculatus and Neotoma lepida. This study comprises the first report of wild rodent serum tested for coccidioidal antibodies, and sets the basis to analyze this pathogen in its natural environment and explore its potential ecological niche.<br /> (Copyright © 2014 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1878-6146
- Volume :
- 118
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Fungal biology
- Publication Type :
- Academic Journal
- Accession number :
- 24607357
- Full Text :
- https://doi.org/10.1016/j.funbio.2014.01.006