Optic neuropathy and blindness associated with crizotinib for non-small-cell lung cancer with EML4-ALK translocation.

Subjects

Subjects :

Adenocarcinoma genetics
Adenocarcinoma pathology
Adenocarcinoma of Lung
Aged
Antineoplastic Agents administration & dosage
Brain Neoplasms complications
Brain Neoplasms diagnosis
Brain Neoplasms genetics
Brain Neoplasms radiotherapy
Brain Neoplasms secondary
Cranial Irradiation
Crizotinib
Disease Progression
Drug Administration Schedule
Female
Humans
Lung Neoplasms genetics
Lung Neoplasms pathology
Magnetic Resonance Imaging
Muscle Weakness etiology
Protein Kinase Inhibitors administration & dosage
Pyrazoles administration & dosage
Pyridines administration & dosage
Signal Transduction drug effects
Adenocarcinoma drug therapy
Antineoplastic Agents adverse effects
Blindness chemically induced
Brain Neoplasms drug therapy
Lung Neoplasms drug therapy
Oncogene Proteins, Fusion genetics
Optic Nerve Diseases chemically induced
Protein Kinase Inhibitors adverse effects
Pyrazoles adverse effects
Pyridines adverse effects
Translocation, Genetic drug effects

Details

Language :

English

ISSN :

1527-7755

Volume :

33

Issue :

5

Database :

MEDLINE

Journal :

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Publication Type :

Academic Journal

Accession number :

24616318

Full Text :

https://doi.org/10.1200/JCO.2013.49.1985