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Hypericin: chemical synthesis and biosynthesis.
- Source :
-
Chinese journal of natural medicines [Chin J Nat Med] 2014 Feb; Vol. 12 (2), pp. 81-8. - Publication Year :
- 2014
-
Abstract
- Hypericin is one of the most important phenanthoperylene quinones extracted mainly from plants of the genus Hypericum belonging to the sections Euhypericum and Campylosporus of Keller's classification. Widespread attention to the antiviral and anti-tumor properties of hypericin has spurred investigations of the chemical synthesis and biosynthesis of this unique compound. However, the synthetic strategies are challenging for organic and biological chemists. In this review, specific significant advances in total synthesis, semi-synthesis, and biosynthesis in the past decades are summarized.<br /> (Copyright © 2014 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1875-5364
- Volume :
- 12
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Chinese journal of natural medicines
- Publication Type :
- Academic Journal
- Accession number :
- 24636057
- Full Text :
- https://doi.org/10.1016/S1875-5364(14)60014-5