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Efficient synthesis of functionalized benzo[b][1,8]naphthyridine derivatives via three-component reaction catalyzed by L-proline.

Authors :
Fu L
Lin W
Hu MH
Liu XC
Huang ZB
Shi DQ
Source :
ACS combinatorial science [ACS Comb Sci] 2014 May 12; Vol. 16 (5), pp. 238-43. Date of Electronic Publication: 2014 Apr 04.
Publication Year :
2014

Abstract

A facile and efficient one-pot procedure for the preparation of functionalized benzo[b][1,8]naphthyridine derivatives by three-component reaction of 2-chloroquinoline-3-carbaldehyde, 1,3-dicarbonyl compounds, and enaminones catalyzed by l-proline is described. This new protocol has the advantages of environmental friendliness, good yields, and convenient operation.

Details

Language :
English
ISSN :
2156-8944
Volume :
16
Issue :
5
Database :
MEDLINE
Journal :
ACS combinatorial science
Publication Type :
Academic Journal
Accession number :
24669887
Full Text :
https://doi.org/10.1021/co4001524