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The effect of respiratory and cardiac motion in liver diffusion tensor imaging (DTI).
- Source :
-
Journal of computer assisted tomography [J Comput Assist Tomogr] 2014 May-Jun; Vol. 38 (3), pp. 352-9. - Publication Year :
- 2014
-
Abstract
- Objective: To evaluate the effect of respiratory and cardiac motion on diffusion tensor imaging (DTI) metrics in healthy human liver.<br />Methods: Fifteen healthy subjects, participating in either part of this study, were scanned using a 1.5-T magnetic resonance imaging (MRI) device. Coronal liver DTI (6 diffusion-encoding directions; b, 300 mm/s) during breath holding was compared to free breathing. Cardiac motion effects were evaluated by comparing breath-held DTI scans acquired during both diastole and systole.<br />Results: Free breathing resulted in a significantly increased mean diffusivity (P < 0.05), λ1 (P < 0.01), λ2 (P < 0.05), and λ3 (P < 0.01) compared to breath holding. During systole significant increases in fractional anisotropy (P < 0.05), mean diffusivity (P < 0.05), and λ1 (P < 0.05), compared to systole, were found in the left lobe. The right lobe, which is less affected by cardiac motion, showed no significant change in DTI metrics over the cardiac cycle.<br />Conclusions: Respiratory and cardiac motion tends to increase liver DTI metrics.
Details
- Language :
- English
- ISSN :
- 1532-3145
- Volume :
- 38
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of computer assisted tomography
- Publication Type :
- Academic Journal
- Accession number :
- 24681854
- Full Text :
- https://doi.org/10.1097/RCT.0000000000000064