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Surgical resection for cancer located mainly in the lower esophagus.
- Source :
-
Hepato-gastroenterology [Hepatogastroenterology] 2013 Nov-Dec; Vol. 60 (128), pp. 1955-60. - Publication Year :
- 2013
-
Abstract
- Background/aims: The aim of the present study was to clarify the results and feasibility of surgical approaches for cancer, which is mainly occupied by squamous cell carcinoma (SCC), of the lower esophagus.<br />Methodology: Forty-four patients (34 men, 10 women) with cancer located at the lower esophagus were enrolled in this study. SCC was diagnosed in 36 cases and adenocarcinoma (ADC) in 8 cases. Thirteen patients underwent transhiatal esophagectomy, 18 underwent lower thoracic esophagectomy by left thoracotomy, and 13 underwent esophagectomy with a right thoracic approach by open thoracotomy or thoracoscopy.<br />Results: Ten cases (ADC, n = 2; SCC, n = 8) showed involvement of mediastinal lymph nodes, although lymph node dissection varied with each surgical approach. Five-year survival rates were 75% for ADC and 31.9% for SCC, and ADC tended to be associated with a more favorable prognosis than SCC (p = 0.058). Transhiatal esophagectomy was performed more often in older patients (p < 0.05), but no other clinicopathological parameters appeared to affect the selection of surgical approach. No significant prognostic differences existed between surgical approaches (p = 0.35), even though the examination was limited to SCC (p = 0.98).<br />Conclusions: No significant prognostic differences were identified between transhiatal and left and right transthoracic approaches for lower esophageal cancer.
- Subjects :
- Adenocarcinoma mortality
Adenocarcinoma pathology
Aged
Aged, 80 and over
Carcinoma, Squamous Cell mortality
Carcinoma, Squamous Cell pathology
Esophageal Neoplasms mortality
Esophageal Neoplasms pathology
Female
Humans
Lymph Node Excision
Lymphatic Metastasis
Male
Middle Aged
Survival Analysis
Time Factors
Treatment Outcome
Adenocarcinoma surgery
Carcinoma, Squamous Cell surgery
Esophageal Neoplasms surgery
Esophagectomy adverse effects
Esophagectomy mortality
Thoracoscopy adverse effects
Thoracoscopy mortality
Thoracotomy adverse effects
Thoracotomy mortality
Subjects
Details
- Language :
- English
- ISSN :
- 0172-6390
- Volume :
- 60
- Issue :
- 128
- Database :
- MEDLINE
- Journal :
- Hepato-gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 24719934