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Corneal collagen cross-linking for Terrien marginal degeneration.
- Source :
-
Journal of refractive surgery (Thorofare, N.J. : 1995) [J Refract Surg] 2014 Jul; Vol. 30 (7), pp. 498-500. Date of Electronic Publication: 2014 Jun 03. - Publication Year :
- 2014
-
Abstract
- Purpose: To report the long-term clinical outcome of a patient diagnosed as having Terrien marginal degeneration (TMD) who was subjected to corneal collagen cross-linking (CXL) with ultraviolet-A and riboflavin in both eyes.<br />Methods: Topographical changes were assessed by high-resolution Scheimpflug imaging and anterior segment optical coherence tomography. Eccentric epithelium-off CXL was performed in both eyes while protecting the corneal limbus. Irradiation was performed with a fluence of 5.4 J/cm(2), using 3 mW/cm(2) for 30 minutes.<br />Results: Five years of postoperative follow-up showed regression of the keratometric values, a local thickening of the corneal stroma, and bilateral improvement of corrected distance visual acuity.<br />Conclusions: CXL may arrest progression in TMD and even reverse the catabolic process in the corneal stroma. CXL might represent an alternative therapeutic approach for the management of TMD.<br /> (Copyright 2014, SLACK Incorporated.)
- Subjects :
- Corneal Dystrophies, Hereditary metabolism
Corneal Dystrophies, Hereditary physiopathology
Corneal Stroma pathology
Corneal Topography
Humans
Male
Middle Aged
Treatment Outcome
Ultraviolet Rays
Visual Acuity physiology
Collagen metabolism
Corneal Dystrophies, Hereditary drug therapy
Corneal Stroma metabolism
Cross-Linking Reagents therapeutic use
Photosensitizing Agents therapeutic use
Riboflavin therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1081-597X
- Volume :
- 30
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Journal of refractive surgery (Thorofare, N.J. : 1995)
- Publication Type :
- Academic Journal
- Accession number :
- 24892378
- Full Text :
- https://doi.org/10.3928/1081597X-20140527-02