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Glucose positions affect the phloem mobility of glucose-fipronil conjugates.
- Source :
-
Journal of agricultural and food chemistry [J Agric Food Chem] 2014 Jul 02; Vol. 62 (26), pp. 6065-71. Date of Electronic Publication: 2014 Jun 19. - Publication Year :
- 2014
-
Abstract
- In our previous work, a glucose-fipronil (GTF) conjugate at the C-1 position was synthesized via click chemistry and a glucose moiety converted a non-phloem-mobile insecticide fipronil into a moderately phloem-mobile insecticide. In the present paper, fipronil was introduced into the C-2, C-3, C-4, and C-6 positions of glucose via click chemistry to obtain four new conjugates and to evaluate the effects of the different glucose isomers on phloem mobility. The phloem mobility of the four new synthetic conjugates and GTF was tested using the Ricinus seedling system. The results confirmed that conjugation of glucose at different positions has a significant influence on the phloem mobility of GTF conjugates.
- Subjects :
- Biological Transport drug effects
Ricinus communis chemistry
Ricinus communis drug effects
Glucose analysis
Glucose pharmacokinetics
Insecticides analysis
Insecticides chemistry
Molecular Structure
Phloem chemistry
Pyrazoles analysis
Pyrazoles pharmacokinetics
Seedlings chemistry
Seedlings drug effects
Ricinus communis metabolism
Glucose analogs & derivatives
Insecticides pharmacokinetics
Phloem metabolism
Pyrazoles chemistry
Seedlings metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1520-5118
- Volume :
- 62
- Issue :
- 26
- Database :
- MEDLINE
- Journal :
- Journal of agricultural and food chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 24918526
- Full Text :
- https://doi.org/10.1021/jf5010429