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Pd(II)-Catalyzed arylation of unactivated methylene C(sp3)-H bonds with aryl halides using a removable auxiliary.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2014 Aug 07; Vol. 50 (61), pp. 8353-5. - Publication Year :
- 2014
-
Abstract
- A Pd(II)-catalyzed arylation of methylene C(sp(3))-H bonds in aliphatic amides directed by our newly developed PIP directing group with aryl iodides/bromides has been achieved. Arylation occurs efficiently with a broad range of aryl halides and amides.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 50
- Issue :
- 61
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 24943091
- Full Text :
- https://doi.org/10.1039/c4cc03615h