Integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 in high-cancer mice under the influence of phytoadaptogen.

Authors :: Bocharova OA
Bocharov EV
Karpova RV
Il'enko VA
Kazeev IV
Baryshnikov AY
Source :: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2014 Jun; Vol. 157 (2), pp. 258-60. Date of Electronic Publication: 2014 Jun 22.
Publication Year :: 2014
Abstract: The expression of leukocyte integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 was studied in mice predisposed to spontaneous hepatocarcinomas. The efficacy of a phytoadaptogen in correcting these parameters was evaluated. The role of adhesive interactions between immune cells and target cells in the recovery of antitumor regulatory mechanisms was estimated.

Subjects :: Animals
Cell Adhesion drug effects
Hepatoblastoma blood
Hepatoblastoma metabolism
Mice
Interleukin-10 blood
Interleukin-6 blood
Lymphocyte Function-Associated Antigen-1 metabolism
Macrophage-1 Antigen metabolism
Plant Extracts pharmacology

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