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The MYB46/MYB83-mediated transcriptional regulatory programme is a gatekeeper of secondary wall biosynthesis.
- Source :
-
Annals of botany [Ann Bot] 2014 Oct; Vol. 114 (6), pp. 1099-107. Date of Electronic Publication: 2014 Jul 01. - Publication Year :
- 2014
-
Abstract
- Background: The secondary cell wall is a defining feature of xylem cells and allows them to resist both gravitational forces and the tension forces associated with the transpirational pull on their internal columns of water. Secondary walls also constitute the majority of plant biomass. Formation of secondary walls requires co-ordinated transcriptional regulation of the genes involved in the biosynthesis of cellulose, hemicellulose and lignin. This co-ordinated control appears to involve a multifaceted and multilayered transcriptional regulatory programme.<br />Scope: Transcription factor MYB46 (At5g12870) has been shown to function as a master regulator in secondary wall formation in Arabidopsis thaliana. Recent studies show that MYB46 not only regulates the transcription factors but also the biosynthesis genes for all of the three major components (i.e. cellulose, hemicellulose and lignin) of secondary walls. This review considers our current understanding of the MYB46-mediated transcriptional regulatory network, including upstream regulators, downstream targets and negative regulators of MYB46.<br />Conclusions and Outlook: MYB46 is a unique transcription factor in that it directly regulates the biosynthesis genes for all of the three major components of the secondary wall as well as the transcription factors in the biosynthesis pathway. As such, MYB46 may offer a useful means for pathway-specific manipulation of secondary wall biosynthesis. However, realization of this potential requires additional information on the 'MYB46-mediated transcriptional regulatory programme', such as downstream direct targets, upstream regulators and interacting partners of MYB46.<br /> (© The Author 2014. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Subjects :
- Arabidopsis metabolism
Arabidopsis Proteins metabolism
Lignin metabolism
Plants, Genetically Modified
Promoter Regions, Genetic genetics
Transcription Factors genetics
Transcription Factors metabolism
Transcriptional Activation
Xylem metabolism
Arabidopsis genetics
Arabidopsis Proteins genetics
Cell Wall metabolism
Gene Expression Regulation, Plant
Subjects
Details
- Language :
- English
- ISSN :
- 1095-8290
- Volume :
- 114
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Annals of botany
- Publication Type :
- Academic Journal
- Accession number :
- 24984711
- Full Text :
- https://doi.org/10.1093/aob/mcu126