Immunophenotypic characterization of canine malignant lymphoma: a retrospective study of cases diagnosed in Poland Lower Silesia, over the period 2011-2013.

Authors :: Pawlak A
Rapak A
Drynda A
Poradowski D
Zbyryt I
Dzimira S
Suchański J
Obmińska-Mrukowicz B
Source :: Veterinary and comparative oncology [Vet Comp Oncol] 2016 Aug; Vol. 14 Suppl 1, pp. 52-60. Date of Electronic Publication: 2014 Jul 23.
Publication Year :: 2016
Abstract: Lymphoma is the most frequently diagnosed cancer of the canine haematopoietic system. In this study, the flow cytometry and polymerase chain reaction (PCR) analysis were used to characterize a series of canine lymphomas in detail. The aim of this study was to determine the incidence of B- and T-cell high-grade lymphomas and their immunophenotypic characterization in Lower Silesia, Poland. The results show that the frequency of each type of lymphoma is 71% for B-cell and 17% for T-cell lymphomas. In two cases the PCR techniques confirmed the presence of simultaneous double gene rearrangements of the BCR and TCR receptors.<br /> (© 2014 John Wiley & Sons Ltd.)

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