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An air-stable cationic iridium hydride as a highly active and general catalyst for the isomerization of terminal epoxides.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2014 Sep 21; Vol. 50 (73), pp. 10592-5. Date of Electronic Publication: 2014 Jul 31. - Publication Year :
- 2014
-
Abstract
- We describe the use of an air-stable iridium hydride catalyst for the isomerization of terminal epoxides into aldehydes with perfect regioselectivity. The system operates at low loadings of catalyst (0.5 mol%), is highly practical, scalable, and tolerates functional groups that would not be compatible with Lewis acids typically used in stoichiometric amounts. Evidence for a rare hydride mechanism are provided.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 50
- Issue :
- 73
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 25078797
- Full Text :
- https://doi.org/10.1039/c4cc05260a