Back to Search
Start Over
Are patients open to elective re-sampling of their glioblastoma? A new way of assessing treatment innovations.
- Source :
-
Acta neurochirurgica [Acta Neurochir (Wien)] 2014 Oct; Vol. 156 (10), pp. 1855-62; discussion 1862-3. Date of Electronic Publication: 2014 Aug 02. - Publication Year :
- 2014
-
Abstract
- Background: This is a qualitative study designed to examine patient acceptability of re-sampling surgery for glioblastoma multiforme (GBM) electively post-therapy or at asymptomatic relapse.<br />Methods: Thirty patients were selected using the convenience sampling method and interviewed. Patients were presented with hypothetical scenarios including a scenario in which the surgery was offered to them routinely and a scenario in which the surgery was in a clinical trial.<br />Results: The results of the study suggest that about two thirds of the patients offered the surgery on a routine basis would be interested, and half of the patients would agree to the surgery as part of a clinical trial. Several overarching themes emerged, some of which include: patients expressed ethical concerns about offering financial incentives or compensation to the patients or surgeons involved in the study; patients were concerned about appropriate communication and full disclosure about the procedures involved, the legalities of tumor ownership and the use of the tumor post-surgery; patients may feel alone or vulnerable when they are approached about the surgery; patients and their families expressed immense trust in their surgeon and indicated that this trust is a major determinant of their agreeing to surgery.<br />Conclusion: The overall positive response to re-sampling surgery suggests that this procedure, if designed with all the ethical concerns attended to, would be welcomed by most patients. This approach of asking patients beforehand if a treatment innovation is acceptable would appear to be more practical and ethically desirable than previous practice.
- Subjects :
- Adult
Aged
Elective Surgical Procedures ethics
Female
Humans
Male
Middle Aged
Neurosurgical Procedures ethics
Qualitative Research
Reoperation ethics
Young Adult
Brain Neoplasms surgery
Elective Surgical Procedures psychology
Glioblastoma surgery
Neurosurgical Procedures psychology
Patient Acceptance of Health Care psychology
Reoperation psychology
Subjects
Details
- Language :
- English
- ISSN :
- 0942-0940
- Volume :
- 156
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Acta neurochirurgica
- Publication Type :
- Academic Journal
- Accession number :
- 25085543
- Full Text :
- https://doi.org/10.1007/s00701-014-2189-3