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A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level.
- Source :
-
International journal of clinical and experimental pathology [Int J Clin Exp Pathol] 2014 Jun 15; Vol. 7 (7), pp. 4467-72. Date of Electronic Publication: 2014 Jun 15 (Print Publication: 2014). - Publication Year :
- 2014
-
Abstract
- Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.
- Subjects :
- Glomerulonephritis physiopathology
Glomerulonephritis virology
Humans
Immune Complex Diseases physiopathology
Immune Complex Diseases virology
Male
Middle Aged
Proteinuria physiopathology
Proteinuria virology
Purpura pathology
Purpura physiopathology
Purpura virology
Glomerulonephritis pathology
HIV Infections complications
Immune Complex Diseases pathology
Immunoglobulin A blood
Subjects
Details
- Language :
- English
- ISSN :
- 1936-2625
- Volume :
- 7
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- International journal of clinical and experimental pathology
- Publication Type :
- Academic Journal
- Accession number :
- 25120835