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A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level.

Authors :
Yang J
Seo MY
Kim KT
Lee JY
Kim SC
Kim MG
Jo SK
Cho WY
Kim HK
Won NH
Cha RH
Cho E
Source :
International journal of clinical and experimental pathology [Int J Clin Exp Pathol] 2014 Jun 15; Vol. 7 (7), pp. 4467-72. Date of Electronic Publication: 2014 Jun 15 (Print Publication: 2014).
Publication Year :
2014

Abstract

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

Details

Language :
English
ISSN :
1936-2625
Volume :
7
Issue :
7
Database :
MEDLINE
Journal :
International journal of clinical and experimental pathology
Publication Type :
Academic Journal
Accession number :
25120835