Wickerhamomyces anomalus fungal keratitis responds to topical treatment with antifungal micafungin.

Authors :: Kamoshita M
Matsumoto Y
Nishimura K
Katono Y
Murata M
Ozawa Y
Shimmura S
Tsubota K
Source :: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2015 Feb; Vol. 21 (2), pp. 141-3. Date of Electronic Publication: 2014 Sep 16.
Publication Year :: 2015
Abstract: We describe a 91-year-old woman who suffered from fungal keratitis after corneal transplantation. The causative organism was identified as Wickerhamomyces anomalus (formerly Pichia anomala or Hansenula anomala) on the basis of morphological characteristics and the sequence of the internal transcribed spacer region of the ribosomal RNA gene. The patient was successfully treated with topical micafungin (MCFG) only. We present the first report of a case of W. anomalus fungal keratitis that responded to topical treatment with the antifungal MCFG.<br /> (Copyright © 2014 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.)

Subjects :: Aged, 80 and over
Eye Infections, Fungal microbiology
Eye Infections, Fungal pathology
Female
Humans
Keratitis microbiology
Keratitis pathology
Micafungin
Antifungal Agents therapeutic use
Echinocandins therapeutic use
Eye Infections, Fungal drug therapy
Keratitis drug therapy
Lipopeptides therapeutic use
Saccharomycetales isolation & purification

Language :: English
ISSN :: 1437-7780
Volume :: 21
Issue :: 2
Database :: MEDLINE
Journal :: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Publication Type :: Academic Journal
Accession number :: 25239058
Full Text :: https://doi.org/10.1016/j.jiac.2014.08.019

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