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Carbapenem resistance in a human clinical isolate identified to be closely related to Acinetobacter indicus.
- Source :
-
International journal of antimicrobial agents [Int J Antimicrob Agents] 2014 Oct; Vol. 44 (4), pp. 345-50. Date of Electronic Publication: 2014 Jul 19. - Publication Year :
- 2014
-
Abstract
- Here we report a case of carbapenem resistance in a human clinical isolate that was found to be closely related to the newly described environmental species Acinetobacter indicus. This strain harboured the blaOXA-23 carbapenemase gene located on a conjugative plasmid. Partial sequencing of 16S rDNA and rpoB genes, together with matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) analysis, showed that this strain was distantly related to the Acinetobacter baumannii-calcoaceticus complex and was closely related to A. indicus.<br /> (Copyright © 2014. Published by Elsevier B.V.)
- Subjects :
- Acinetobacter chemistry
Acinetobacter isolation & purification
Cluster Analysis
DNA, Bacterial chemistry
DNA, Bacterial genetics
DNA, Ribosomal chemistry
DNA, Ribosomal genetics
DNA-Directed RNA Polymerases genetics
Humans
Male
Molecular Sequence Data
Phylogeny
Plasmids
RNA, Ribosomal, 16S genetics
Sequence Analysis, DNA
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
beta-Lactamases genetics
Acinetobacter classification
Acinetobacter drug effects
Acinetobacter Infections microbiology
Anti-Bacterial Agents pharmacology
Carbapenems pharmacology
beta-Lactam Resistance
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7913
- Volume :
- 44
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- International journal of antimicrobial agents
- Publication Type :
- Academic Journal
- Accession number :
- 25245212
- Full Text :
- https://doi.org/10.1016/j.ijantimicag.2014.05.022