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Regular intermittent bolus provides similar incidence of maternal fever compared with continuous infusion during epidural labor analgesia.
- Source :
-
Saudi medical journal [Saudi Med J] 2014 Oct; Vol. 35 (10), pp. 1237-42. - Publication Year :
- 2014
-
Abstract
- Objectives: To compare the effects of regular intermittent bolus versus continuous infusion for epidural labor analgesia on maternal temperature and serum interleukin-6 (IL-6) level.<br />Methods: This randomized trial was performed in Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu Province, China between October 2012 and February 2014. Either regular intermittent bolus (RIB, n=66) or continuous infusion (CI, n=66) was used for epidural labor analgesia. A bolus dose (10 ml of 0.08% ropivacaine + 0.4 ug·ml-1 sufentanil) was manually administrated once an hour in the RIB group, whereas the same solution was continuously infused at a constant rate of 10 ml·h-1 in the CI group. Maternal tympanic temperature and serum IL-6 level were measured hourly from baseline to one hour post partum. The incidences of fever (&gt;/=38 degree celsius ) were calculated.<br />Results: The incidence of maternal fever was similar between the 2 groups. There was a rising trend in mean temperature over time in both groups, but no statistical difference was detected between the groups at respective time points; maternal serum IL-6 showed similar changes.<br />Conclusion: Compared with continuous infusion, regular intermittent bolus presents with the same incidence of maternal fever for epidural labor analgesia. Interleukin-6 elevation could be involved in mean maternal temperature increase.
- Subjects :
- Adult
Analgesia, Epidural methods
Analgesia, Obstetrical methods
Double-Blind Method
Female
Fever blood
Humans
Incidence
Infusions, Spinal
Obstetric Labor Complications blood
Pregnancy
Ropivacaine
Young Adult
Amides administration & dosage
Analgesics, Opioid administration & dosage
Anesthetics, Local administration & dosage
Fever epidemiology
Interleukin-6 blood
Obstetric Labor Complications epidemiology
Sufentanil administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1658-3175
- Volume :
- 35
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Saudi medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 25316469