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Adverse effects of androgen-deprivation therapy in prostate cancer and their management.
- Source :
-
BJU international [BJU Int] 2015 Apr; Vol. 115 Suppl 5, pp. 3-13. - Publication Year :
- 2015
-
Abstract
- Objective: To provide an up-to-date summary of current literature on the management of adverse effects of androgen-deprivation therapy (ADT).<br />Patients and Methods: All relevant medical literature on men with prostate cancer treated with ADT from 2005 to 2014, and older relevant papers, were reviewed. Recent health advisory statements from the Australian government, societies and advocacy groups have been incorporated to the document.<br />Results: There are numerous adverse effects of ADT that require pro-active prevention and treatment. Ranging from cardiovascular disease, diabetes and osteoporosis, to depression, cognitive decline and sexual dysfunction, the range of adverse effects is wide. Baseline assessment, monitoring, prevention and consultation from a multidisciplinary team are important in minimising the harm from ADT.<br />Conclusions: This review provides a series of practical recommendations to assist with managing the adverse effects of ADT.<br /> (© 2014 The Authors. BJU International © 2014 BJU International.)
- Subjects :
- Androgen Antagonists therapeutic use
Antineoplastic Agents therapeutic use
Drug-Related Side Effects and Adverse Reactions prevention & control
Humans
Male
Androgen Antagonists adverse effects
Antineoplastic Agents adverse effects
Drug-Related Side Effects and Adverse Reactions therapy
Prostatic Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1464-410X
- Volume :
- 115 Suppl 5
- Database :
- MEDLINE
- Journal :
- BJU international
- Publication Type :
- Academic Journal
- Accession number :
- 25327530
- Full Text :
- https://doi.org/10.1111/bju.12964