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Incidence of and risk factors for Alzheimer's disease and mild cognitive impairment in Korean elderly.
- Source :
-
Dementia and geriatric cognitive disorders [Dement Geriatr Cogn Disord] 2015; Vol. 39 (1-2), pp. 105-15. Date of Electronic Publication: 2014 Nov 11. - Publication Year :
- 2015
-
Abstract
- Background/aims: Knowledge of incidence rates and risk factors is essential for the development of strategies to treat patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI).<br />Methods: A subpopulation of the Nationwide Survey on Dementia Epidemiology (460 Korean subjects aged ≥65 years from 2 rural and 2 urban districts) was followed up for 3.5 years. The age-specific incidence was estimated and risk factors were identified.<br />Results: The age-standardized incidence of AD and MCI was 7.9 and 28.1 cases per 1,000 person-years, respectively. MCI was associated with a 6-fold increased risk of AD. Depression was a risk factor for AD with MCI. Age, lack of formal education, illiteracy, rural residence, and marital status were associated with the risk of AD.<br />Conclusion: Strategies to control modifiable risk factors should be implemented to decrease the incidence of AD.<br /> (© 2014 S. Karger AG, Basel.)
Details
- Language :
- English
- ISSN :
- 1421-9824
- Volume :
- 39
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Dementia and geriatric cognitive disorders
- Publication Type :
- Academic Journal
- Accession number :
- 25401488
- Full Text :
- https://doi.org/10.1159/000366555