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Comparative study of conductometric glucose biosensor based on gold and on magnetic nanoparticles.
- Source :
-
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2013 Jan 01; Vol. 33 (1), pp. 298-303. Date of Electronic Publication: 2012 Sep 11. - Publication Year :
- 2013
-
Abstract
- The aim of this study was to show the feasibility and the performances of nanoparticle biosensing. A glucose conductometric biosensor was developed using two types of nanoparticles (gold and magnetic), glucose oxidase (GOD) being adsorbed on PAH (poly(allylamine hydrochloride)) modified nanoparticles, deposited on a planar interdigitated electrode (IDEs). The best sensitivities for glucose detection were obtained with magnetic nanoparticles (70 μM/mM and 3 μM of detection limit) compared to 45 μM/mM and 9 μM with gold nanoparticles and 30 μM/mM and 50 μM with GOD directly cross-linked on IDEs. When stored in phosphate buffer (20 mM, pH 7.3) at 4 °C, the biosensor showed good stability for more than 12 days.<br /> (Copyright © 2012 Elsevier B.V. All rights reserved.)
- Subjects :
- Biosensing Techniques
Electrodes
Enzymes, Immobilized chemistry
Enzymes, Immobilized metabolism
Glucose Oxidase chemistry
Glucose Oxidase metabolism
Magnetite Nanoparticles ultrastructure
Microscopy, Electron, Transmission
Polyamines chemistry
Conductometry
Glucose analysis
Gold chemistry
Magnetite Nanoparticles chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1873-0191
- Volume :
- 33
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Materials science & engineering. C, Materials for biological applications
- Publication Type :
- Academic Journal
- Accession number :
- 25428075
- Full Text :
- https://doi.org/10.1016/j.msec.2012.08.043