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Autologous stem cell transplantation in multiple myeloma is not dead but alive and well.
- Source :
-
Expert opinion on biological therapy [Expert Opin Biol Ther] 2015 Feb; Vol. 15 (2), pp. 149-54. Date of Electronic Publication: 2014 Nov 29. - Publication Year :
- 2015
-
Abstract
- In multiple myeloma (MM), the use of high-dose chemotherapy with autologous stem cell transplantation (ASCT) led to incremental advances in patient management in the 1990s. The clinical results for patients dramatically improved further in the 2000s with the introduction of immunomodulatory drugs and proteasome inhibitors. In the 'modern' era for MM treatment, transplant trials strongly support the use of upfront ASCT in the context of novel agents, and until proven otherwise, the old ASCT remains the standard of care for eligible patients. Nevertheless, some issues remain unresolved and this editorial aims to highlight the concerns to be addressed in the future.
Details
- Language :
- English
- ISSN :
- 1744-7682
- Volume :
- 15
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Expert opinion on biological therapy
- Publication Type :
- Editorial & Opinion
- Accession number :
- 25435056
- Full Text :
- https://doi.org/10.1517/14712598.2015.988611