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Cognitive status in patients hospitalized with acute decompensated heart failure.
- Source :
-
American heart journal [Am Heart J] 2014 Dec; Vol. 168 (6), pp. 917-23. Date of Electronic Publication: 2014 Sep 16. - Publication Year :
- 2014
-
Abstract
- Background: Cognitive impairment is highly prevalent in patients with heart failure and is associated with adverse outcomes. However, whether specific cognitive abilities (eg, memory vs executive function) are impaired in heart failure has not been fully examined. We investigated the prevalence of impairment in 3 cognitive domains in patients hospitalized with acute decompensated heart failure (ADHF) and the associations of impairment with demographic and clinical characteristics.<br />Methods: The sample included 744 patients hospitalized with ADHF (mean age 72 years, 46% female) at 5 medical centers. Impairment was assessed in 3 cognitive domains (memory, processing speed, executive function) using standardized measures. Demographic and clinical characteristics were obtained from a structured interview and medical record review.<br />Results: A total of 593 (80%) of 744 patients were impaired in at least 1 cognitive domain; 32%, 31%, and 17% of patients were impaired in 1, 2, or all 3 cognitive domains, respectively. Patients impaired in more than 1 cognitive domain were significantly older, had less formal education, and had more noncardiac comorbidities (all P values < .05). In multivariable adjusted analyses, patients with older age and lower education had higher odds of impairment in 2 or more cognitive domains. Depressed patients had twice the odds of being impaired in all 3 cognitive domains (odds ratio 1.98, 95% CI 1.08-3.64).<br />Conclusion: Impairments in executive function, processing speed, and memory are common among patients hospitalized for ADHF. Recognition of these prevalent cognitive deficits is critical for the clinical management of these high-risk patients.<br /> (Copyright © 2014 Elsevier Inc. All rights reserved.)
- Subjects :
- Acute Disease
Aged
Canada epidemiology
Demography
Female
Geriatric Assessment methods
Humans
Interview, Psychological
Male
Medical Records, Problem-Oriented
Neuropsychological Tests
Prevalence
Risk Factors
Cognition Disorders diagnosis
Cognition Disorders epidemiology
Cognition Disorders etiology
Cognition Disorders physiopathology
Executive Function
Heart Failure complications
Heart Failure epidemiology
Heart Failure physiopathology
Heart Failure psychology
Heart Failure therapy
Hospitalization statistics & numerical data
Memory Disorders diagnosis
Memory Disorders etiology
Memory Disorders physiopathology
Psychomotor Performance
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6744
- Volume :
- 168
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- American heart journal
- Publication Type :
- Academic Journal
- Accession number :
- 25458656
- Full Text :
- https://doi.org/10.1016/j.ahj.2014.08.008