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Tenascin-C: Form versus function.
- Source :
-
Cell adhesion & migration [Cell Adh Migr] 2015; Vol. 9 (1-2), pp. 48-82. - Publication Year :
- 2015
-
Abstract
- Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very restricted pattern of expression but an enormously diverse range of functions. Here, we discuss the importance of deciphering the expression pattern of, and effects mediated by, different forms of this molecule in order to fully understand tenascin-C biology. We focus on both post transcriptional and post translational events such as splicing, glycosylation, assembly into a 3D matrix and proteolytic cleavage, highlighting how these modifications are key to defining tenascin-C function.
Details
- Language :
- English
- ISSN :
- 1933-6926
- Volume :
- 9
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Cell adhesion & migration
- Publication Type :
- Academic Journal
- Accession number :
- 25482829
- Full Text :
- https://doi.org/10.4161/19336918.2014.987587