A new low-frequency alloantigen (Kha(b) ) located on platelet glycoprotein IIIa as a cause of maternal sensitization leading to neonatal alloimmune thrombocytopenia.

Authors :: Sullivan MJ
Peterson J
McFarland JG
Bougie D
Aster RH
Curtis BR
Source :: Transfusion [Transfusion] 2015 Jun; Vol. 55 (6 Pt 2), pp. 1584-5. Date of Electronic Publication: 2014 Dec 15.
Publication Year :: 2015
Abstract: Competing Interests: All authors declare no conflicts of interest relevant to the content of this manuscript.

Subjects :: Antigens, Human Platelet genetics
Female
Gene Frequency
HEK293 Cells
Humans
Infant, Newborn
Isoantigens genetics
Isoantigens immunology
Polymorphism, Single Nucleotide
Pregnancy
Rh Isoimmunization genetics
Thrombocytopenia, Neonatal Alloimmune genetics
Antigens, Human Platelet immunology
Integrin beta3 genetics
Integrin beta3 immunology
Isoantigens blood
Rh Isoimmunization immunology
Thrombocytopenia, Neonatal Alloimmune immunology

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