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Persistence of West Nile virus.
- Source :
-
Microbes and infection [Microbes Infect] 2015 Feb; Vol. 17 (2), pp. 163-8. Date of Electronic Publication: 2014 Dec 11. - Publication Year :
- 2015
-
Abstract
- West Nile virus (WNV) is a widespread global pathogen that results in significant morbidity and mortality. Data from animal models provide evidence of persistent renal and neurological infection from WNV; however, the possibility of persistent infection in humans and long-term neurological and renal outcomes related to viral persistence remain largely unknown. In this paper, we provide a review of the literature related to persistent infection in parallel with the findings from cohorts of patients with a history of WNV infection. The next steps for enhancing our understanding of WNV as a persistent pathogen are discussed.<br /> (Copyright © 2014 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Animals
Disease Models, Animal
Humans
Renal Insufficiency, Chronic mortality
United States epidemiology
West Nile Fever complications
West Nile Fever prevention & control
Renal Insufficiency, Chronic virology
West Nile Fever virology
West Nile virus isolation & purification
West Nile virus pathogenicity
Subjects
Details
- Language :
- English
- ISSN :
- 1769-714X
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Microbes and infection
- Publication Type :
- Academic Journal
- Accession number :
- 25499188
- Full Text :
- https://doi.org/10.1016/j.micinf.2014.12.003