Supramolecular intracellular delivery of an anionic porphyrin by octaarginine-conjugated per-O-methyl-β-cyclodextrin.

Authors :: Kitagishi H
Chai F
Negi S
Sugiura Y
Kano K
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Feb 11; Vol. 51 (12), pp. 2421-4.
Publication Year :: 2015
Abstract: A convenient and efficient method for intracellular delivery of a water-soluble anionic porphyrin has been developed by utilizing its supramolecular interaction with per-O-methyl-β-cyclodextrin bearing an octaarginine chain as a cell-penetrating peptide.

Subjects :: Anions chemistry
Catalysis
Cell Survival drug effects
Cell-Penetrating Peptides chemistry
Copper chemistry
Flow Cytometry
HeLa Cells
Humans
Porphyrins metabolism
Porphyrins toxicity
Oligopeptides chemistry
Porphyrins chemistry
beta-Cyclodextrins chemistry

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