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Longitudinal comparison of outcomes after sub-Bowman keratomileusis and laser in situ keratomileusis: randomized, double-masked study.
- Source :
-
American journal of ophthalmology [Am J Ophthalmol] 2015 May; Vol. 159 (5), pp. 835-45.e3. Date of Electronic Publication: 2015 Feb 11. - Publication Year :
- 2015
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Abstract
- Purpose: To compare the outcomes of sub-Bowman keratomileusis (100-μm flap) and laser in situ keratomileusis (LASIK) (120-μm flap) using 150-kHz femtosecond laser.<br />Design: Randomized, double-masked, contralateral clinical trial.<br />Methods: One hundred patients (200 eyes) with myopia or myopic astigmatism were included. Postoperative examinations were performed at week 1 and months 1, 3, 6, and 12. Main outcome measures included postoperative uncorrected (UCVA) and best-corrected distance visual acuity (BCVA); manifest refraction spherical equivalent; efficacy and safety indices; corneal thickness; and complications.<br />Results: The mean age of patients was 33.9 ± 7.9 years. Overall, the preoperative UCVA, BCVA, and manifest refraction spherical equivalent were 1.349 ± 0.332, -0.022 ± 0.033, and -5.81 ± 1.61 diopters, respectively. No significant difference was observed in preoperative (P ≥ .226) or intraoperative parameters (P ≥ .452) between both groups, except residual stromal thickness (P < .001). The UCVA, manifest refraction spherical equivalent, and central corneal thickness stabilized by 1 week, while the thinnest corneal thickness stabilized by 3 months postoperatively. There was no significant difference between both groups for any parameter during all follow-up visits (P ≥ .132) except the 3-month safety index, which was better in the sub-Bowman keratomileusis group (P = .007). Soft opaque bubble layer was noted intraoperatively in 12 cases (7, 100-μm group; 5, 120-μm group; P = .577). No postoperative complications were observed.<br />Conclusions: Our study did not find any differences in the visual and refractive outcomes between femtosecond-assisted sub-Bowman keratomileusis and LASIK. Both surgeries resulted in quick visual recovery as early as 1 week postoperatively.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Astigmatism physiopathology
Corneal Pachymetry
Double-Blind Method
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myopia physiopathology
Refraction, Ocular physiology
Visual Acuity physiology
Young Adult
Astigmatism surgery
Bowman Membrane surgery
Keratomileusis, Laser In Situ methods
Lasers, Excimer therapeutic use
Myopia surgery
Surgical Flaps
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1891
- Volume :
- 159
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- American journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 25681001
- Full Text :
- https://doi.org/10.1016/j.ajo.2015.02.003