Back to Search
Start Over
A new path to leukemia with WIT.
- Source :
-
Molecular cell [Mol Cell] 2015 Feb 19; Vol. 57 (4), pp. 573-574. - Publication Year :
- 2015
-
Abstract
- In this issue, Wang et al., 2015 describes that WT1 recruits TET2 to the DNA, an important feature of a new regulatory pathway linked to the development of acute myeloid leukemia (AML). This pathway consists of WT1, IDH1/2, and TET2 (WIT) genes, with exclusive mutations of the three genes inducing myeloid cell proliferation.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1097-4164
- Volume :
- 57
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Molecular cell
- Publication Type :
- Academic Journal
- Accession number :
- 25699704
- Full Text :
- https://doi.org/10.1016/j.molcel.2015.02.005