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[Preoperative chemotherapy enabled radical resection of tumors in a patient with multiple liver metastases].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2014 Nov; Vol. 41 (12), pp. 1743-5. - Publication Year :
- 2014
-
Abstract
- The patient was a 61-year-old man with a prominent epigastric mass and dull pain. Sigmoid colon cancer and multiple hepatic metastases were diagnosed upon examination. The liver metastases were adjacent to the right hepatic artery and the portal vein; therefore, the patient received preoperative bevacizumab+XELOX (capecitabine plus oxaliplatin) chemotherapy. After 6 courses of chemotherapy, a sufficient partial response (PR) was achieved to secure a surgical margin during radical resection of the tumors. The patient is alive, without recurrence, 10 months after surgery. This report highlights the importance of securing a surgical margin during conversion therapy and reviews evidence from previous literature reports.
- Subjects :
- Antibodies, Monoclonal, Humanized administration & dosage
Antineoplastic Combined Chemotherapy Protocols administration & dosage
Bevacizumab
Capecitabine
Combined Modality Therapy
Deoxycytidine administration & dosage
Deoxycytidine analogs & derivatives
Fluorouracil administration & dosage
Fluorouracil analogs & derivatives
Humans
Liver Neoplasms secondary
Liver Neoplasms surgery
Male
Middle Aged
Oxaloacetates
Sigmoid Neoplasms pathology
Sigmoid Neoplasms surgery
Treatment Outcome
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Liver Neoplasms drug therapy
Sigmoid Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 41
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 25731315