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Clinical reversible myelopathy in T-cell lymphoblastic lymphoma treated with nelarabine and radiotherapy: report of a case and review of literature of an increasing complication.
- Source :
-
Mediterranean journal of hematology and infectious diseases [Mediterr J Hematol Infect Dis] 2015 Mar 01; Vol. 7 (1), pp. e2015025. Date of Electronic Publication: 2015 Mar 01 (Print Publication: 2015). - Publication Year :
- 2015
-
Abstract
- Eleven cases of neurological defects in T-ALL patients treated with nelarabine have been described in the last 4 years, seven of these after stem cell transplantation (SCT) for T Lymphoblastic Lymphoma (T-LBL). Most of these patients had an unfavorable outcome or irreversible neurological damage. We now report the case of a 41-year-old woman suffering from T-LBL who presented with severe, but reversible myelopathy after receiving nelarabine-based treatment and mediastinal radiotherapy, and we provide a review of the literature on the topic.
Details
- Language :
- English
- ISSN :
- 2035-3006
- Volume :
- 7
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Mediterranean journal of hematology and infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 25745552
- Full Text :
- https://doi.org/10.4084/MJHID.2015.025