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Recommendations for cardiomyopathy surveillance for survivors of childhood cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.
- Source :
-
The Lancet. Oncology [Lancet Oncol] 2015 Mar; Vol. 16 (3), pp. e123-36. - Publication Year :
- 2015
-
Abstract
- Survivors of childhood cancer treated with anthracycline chemotherapy or chest radiation are at an increased risk of developing congestive heart failure. In this population, congestive heart failure is well recognised as a progressive disorder, with a variable period of asymptomatic cardiomyopathy that precedes signs and symptoms. As a result, several clinical practice guidelines have been developed independently to help with detection and treatment of asymptomatic cardiomyopathy. These guidelines differ with regards to definitions of at-risk populations, surveillance modality and frequency, and recommendations for interventions. Differences between these guidelines could hinder the effective implementation of these recommendations. We report on the results of an international collaboration to harmonise existing cardiomyopathy surveillance recommendations using an evidence-based approach that relied on standardised definitions for outcomes of interest and transparent presentation of the quality of the evidence. The resultant recommendations were graded according to the quality of the evidence and the potential benefit gained from early detection and intervention.<br /> (Copyright © 2015 Elsevier Ltd. All rights reserved.)
- Subjects :
- Adult
Age Factors
Biomarkers blood
Cardiomyopathies blood
Cardiomyopathies chemically induced
Cardiomyopathies therapy
Child
Child, Preschool
Consensus
Cooperative Behavior
Early Diagnosis
Echocardiography standards
Evidence-Based Medicine
Humans
International Cooperation
Magnetic Resonance Imaging standards
Predictive Value of Tests
Radiation Injuries blood
Radiation Injuries etiology
Radiation Injuries therapy
Radionuclide Angiography standards
Radiotherapy adverse effects
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome
Anthracyclines adverse effects
Antibiotics, Antineoplastic adverse effects
Cardiomyopathies diagnosis
Diagnostic Imaging standards
Neoplasms drug therapy
Neoplasms radiotherapy
Radiation Injuries diagnosis
Survivors
Subjects
Details
- Language :
- English
- ISSN :
- 1474-5488
- Volume :
- 16
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Lancet. Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 25752563
- Full Text :
- https://doi.org/10.1016/S1470-2045(14)70409-7