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The role of uncertainty regarding the results of screening immunoassays in blood establishments.
- Source :
-
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [Transfus Apher Sci] 2015 Apr; Vol. 52 (2), pp. 252-5. Date of Electronic Publication: 2015 Feb 14. - Publication Year :
- 2015
-
Abstract
- The risk of uncertain results in infectious agents' tests is recognized in blood establishments, being particularly evident during the blood donor selection. The current risk-based approaches require risk assessment and "risk-based thinking". Accordingly, the blood establishment should consider the effect of uncertainty in all the technical decisions taken in a screening laboratory. Since the post-transfusion safety is one of the blood establishments' goals, the risk of post-transfusion infection should be evaluated and actions taken to decrease the chance of blood donations validation use false negative results. This article reviews and discusses the sources of uncertainty of infectious agents' reported results in blood establishments. It describes a set of sources of uncertainty that should be considered in screening immunoassay's decisions. The infectious agents' uncertainty concern is critical for reporting reliable results.<br /> (Copyright © 2015 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1473-0502
- Volume :
- 52
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
- Publication Type :
- Academic Journal
- Accession number :
- 25754470
- Full Text :
- https://doi.org/10.1016/j.transci.2015.02.015