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Medical versus surgical management for emphysematous pancreatic necrosis: is gas within pancreatic necrosis an absolute indication for surgery?
- Source :
-
Pancreas [Pancreas] 2015 Jul; Vol. 44 (5), pp. 808-11. - Publication Year :
- 2015
-
Abstract
- Objectives: The aim of this study was to evaluate whether pancreatic necrosis with presence of gas is an absolute indication for surgery or if there is a possibility for the medical management of this pathology.<br />Methods: This study is a retrospective study including 56 patients with diagnosis of pancreatic necrosis and gas on computed tomography from April 2003 to March 2011. We recorded all the factors related to each group of treatment, including APACHE II score, C-reactive protein level, Tomographic Severity Index, organ and multiorgan failure, and infected necrosis after fine-needle puncture, to evaluate the differences between surgical and medical treatment.<br />Results: Thirty-six (64%) of these patients were submitted to surgery, whereas 20 (36%) were managed conservatively. Twenty-eight patients (78%) who underwent surgery had infected necrosis. Thirty-five percent of the patients (7 patients) in the medical group had organ failure versus 83% of the patients in the surgical group.<br />Conclusions: Pancreatic necrosis with gas on computed tomography is a relative indication for surgery. Medical management is a feasible and safe possibility for this pathology in selected cases. The presence of organ failure and infected necrosis often precludes a surgical treatment.
- Subjects :
- APACHE
Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers analysis
Biopsy, Fine-Needle
C-Reactive Protein analysis
Emphysema blood
Emphysema diagnosis
Emphysema microbiology
Emphysema surgery
Female
Gases
Humans
Male
Middle Aged
Multiple Organ Failure microbiology
Multiple Organ Failure therapy
Pancreatitis, Acute Necrotizing blood
Pancreatitis, Acute Necrotizing diagnosis
Pancreatitis, Acute Necrotizing microbiology
Pancreatitis, Acute Necrotizing surgery
Patient Selection
Predictive Value of Tests
Retrospective Studies
Risk Factors
Tomography, X-Ray Computed
Treatment Outcome
Young Adult
Emphysema therapy
Pancreatectomy adverse effects
Pancreatitis, Acute Necrotizing therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1536-4828
- Volume :
- 44
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Pancreas
- Publication Type :
- Academic Journal
- Accession number :
- 25760427
- Full Text :
- https://doi.org/10.1097/MPA.0000000000000322