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A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis.
- Source :
-
Journal of infection in developing countries [J Infect Dev Ctries] 2015 Mar 15; Vol. 9 (3), pp. 317-20. Date of Electronic Publication: 2015 Mar 15. - Publication Year :
- 2015
-
Abstract
- This study described some essential viral and sera-characteristics of A/H7N9 virus infection in a 61-year old case patient. With the antiviral therapy and respiratory support, the patient showed a significant decrease of viral loads from 6.72 log10 copies/mL to 0 in 22 days, and a correlated increase of serum hemagglutination inhibition titers during the same period. Phylogenetic analysis demonstrated that the isolated strain was highly homologous to previous strains isolated in the southeast of China. Drug resistance-associated R292K mutation became detectable 17 days after antiviral therapy, but no remarkable influence on the viral clearance was observed.
- Subjects :
- Antibodies, Viral blood
Antiviral Agents therapeutic use
China
Drug Resistance, Viral
Extracorporeal Membrane Oxygenation
Female
Hemagglutination Inhibition Tests
Humans
Influenza, Human therapy
Middle Aged
Mutation, Missense
Time
Treatment Outcome
Viral Load
Influenza A Virus, H7N9 Subtype isolation & purification
Influenza, Human diagnosis
Influenza, Human virology
Subjects
Details
- Language :
- English
- ISSN :
- 1972-2680
- Volume :
- 9
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of infection in developing countries
- Publication Type :
- Academic Journal
- Accession number :
- 25771472
- Full Text :
- https://doi.org/10.3855/jidc.5875