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Conservative management of preterm premature rupture of membranes beyond 32 weeks' gestation: is it worthwhile?
- Source :
-
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology [J Obstet Gynaecol] 2015; Vol. 35 (6), pp. 585-90. Date of Electronic Publication: 2015 Mar 16. - Publication Year :
- 2015
-
Abstract
- We aimed to investigate whether conservative management of preterm premature rupture of membranes (PPROM) at 32-34 weeks' gestation improves outcome. In this retrospective analysis of singleton pregnancies, the study group included patients with PPROM at 28-34 weeks' gestation and the control group included patients presented with spontaneous preterm delivery at 28-34 weeks' gestation. Both groups were subdivided according to gestational age - early (28-31 weeks' gestation) versus late (32-34 weeks' gestation). Adverse neonatal outcome included neonatal death, intraventricular haemorrhage grade 3/4, respiratory distress syndrome, periventricular leucomalacia and neonatal sepsis. The study and control groups included 94 and 86 women, respectively. The study group had a lower incidence of adverse neonatal outcome at the earlier weeks (28-31), compared with the control group at the same gestational age. In contrast, at 32-34 weeks' gestation no difference in the risk for adverse neonatal outcome was noticed. Additionally, within the study group, chorioamnionitis rate was significantly higher among those who delivered at 32-34 weeks' gestation (p < 0.01). No advantage for conservative management of PPROM was demonstrated beyond 31 weeks' gestation. Moreover, conservative management of PPROM at 32-34 weeks' gestation may expose both mother and neonate to infectious morbidity.
- Subjects :
- Cesarean Section statistics & numerical data
Chorioamnionitis epidemiology
Female
Fetal Membranes, Premature Rupture epidemiology
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases epidemiology
Length of Stay
Pregnancy
Premature Birth epidemiology
Retrospective Studies
Fetal Membranes, Premature Rupture therapy
Gestational Age
Pregnancy Outcome
Treatment Outcome
Subjects
Details
- Language :
- English
- ISSN :
- 1364-6893
- Volume :
- 35
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
- Publication Type :
- Academic Journal
- Accession number :
- 25774537
- Full Text :
- https://doi.org/10.3109/01443615.2014.990432