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[Case of graves' disease with remarkable psychiatric symptoms].
- Source :
-
Journal of UOEH [J UOEH] 2015 Mar 01; Vol. 37 (1), pp. 49-53. - Publication Year :
- 2015
-
Abstract
- A 42-year-old woman visited our hospital with palpitations, excessive sweating, and finger tremors in March 2011. She was diagnosed with Graves' disease based on the following test results: thyroid stimulating hormone < 0.01 μU/ml, free thyroxine 6.15 ng/ml, and thyrotropin receptor antibody 7.8 U/ml. Treatment with methimazole 30 mg and propranolol 30 mg was started, and her thyroid function showed improvement. However, significant manic symptoms, irritability, hallucinations, and delusions were noted, and she was hospitalized for her own protection in May 2011. Although treatment with aripiprazole 24 mg and lithium 400 mg was started, the hallucinatory and delusional symptoms persisted, necessitating adjustment of the antipsychotics. Her psychiatric symptoms showed amelioration in July 2011 after improvement in her thyroid function, and she was discharged from our hospital. After discharge, her thyroid function remained normal with methimazole 10 mg, and administration of the antipsychotics was discontinued. Affective psychotic symptoms such as altered mood and activity are frequently observed in cases with Graves' disease, but there have been few reports describing cases with full-blown psychiatric disorders manifesting with features such as hallucinations and delusions as the chief symptoms requiring hospitalized treatment, as in the present case. In symptomatic psychosis associated with Graves' disease, prolonged psychiatric symptoms might develop, and close cooperation with psychiatrists is thus important.
- Subjects :
- Adult
Affective Disorders, Psychotic therapy
Antipsychotic Agents administration & dosage
Antithyroid Agents administration & dosage
Aripiprazole
Bipolar Disorder therapy
Delusions therapy
Female
Hallucinations therapy
Humans
Lithium Compounds administration & dosage
Methimazole administration & dosage
Piperazines administration & dosage
Propranolol administration & dosage
Quinolones administration & dosage
Treatment Outcome
Affective Disorders, Psychotic etiology
Bipolar Disorder etiology
Delusions etiology
Graves Disease complications
Hallucinations etiology
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0387-821X
- Volume :
- 37
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of UOEH
- Publication Type :
- Academic Journal
- Accession number :
- 25787102
- Full Text :
- https://doi.org/10.7888/juoeh.37.49