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[Investigation of pollution characteristics of erythromycin resistance genes in a sewage treatment plant and the relevant selective factors].
- Source :
-
Huan jing ke xue= Huanjing kexue [Huan Jing Ke Xue] 2014 Dec; Vol. 35 (12), pp. 4589-95. - Publication Year :
- 2014
-
Abstract
- Occurrence and distribution of twelve pharmaceutical and personal care products (PPCPs) were investigated in a sewage treatment plant in Shanghai using solid-phase extraction combined with high-performance liquid chromatography-tandem mass spectrometry (SPE-HPLC-MS/MS). Quantitative PCR (qPCR) was used to determine the distribution and removal of seven erythromycin resistance genes (ERY-ARGs). The results showed that five PPCPs including sulfamethoxazole, erythromycin, tetracycline, carbamazepine and triclosan were detected in the collected wastewater samples with concentrations in the ranges of 24.5- 38.7, 47.5-49.2, 43.1-85.4, 2.5-3.9 and 423.2-8 973.3 ng x L(-1), respectively. During the wastewater treatment process, a significant reduction of triclosan was observed, but the removal efficiencies for the other detected PPCPs were relatively low. Additionally, all target ERY-ARGs were detected in the wastewater samples ranging from 9.28 x 10(3) (ermA) to 1.83 x 10(8) (ereA) copies x L(-1) in raw influent. Though significant reductions (1.19 log-3.97 log) of ERY-ARGs were obtained, their concentrations found in the final effluent were still high. Moreover, the concentration of ERY-ARGs exhibited significant positive correlation with the concentration of erythromycin and triclosan (P < 0.05), respectively, elucidating that erythromycin played an important role in the occurrence and spread of ERY-ARGs, while triclosan may confer cross-selection for ERY-ARGs.
Details
- Language :
- Chinese
- ISSN :
- 0250-3301
- Volume :
- 35
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Huan jing ke xue= Huanjing kexue
- Publication Type :
- Academic Journal
- Accession number :
- 25826929