Paediatric CT protocol optimisation: a design of experiments to support the modelling and optimisation process.

Authors :: Rani K
Jahnen A
Noel A
Wolf D
Source :: Radiation protection dosimetry [Radiat Prot Dosimetry] 2015 Jul; Vol. 165 (1-4), pp. 205-9. Date of Electronic Publication: 2015 Apr 05.
Publication Year :: 2015
Abstract: In the last decade, several studies have emphasised the need to understand and optimise the computed tomography (CT) procedures in order to reduce the radiation dose applied to paediatric patients. To evaluate the influence of the technical parameters on the radiation dose and the image quality, a statistical model has been developed using the design of experiments (DOE) method that has been successfully used in various fields (industry, biology and finance) applied to CT procedures for the abdomen of paediatric patients. A Box-Behnken DOE was used in this study. Three mathematical models (contrast-to-noise ratio, noise and CTDI vol) depending on three factors (tube current, tube voltage and level of iterative reconstruction) were developed and validated. They will serve as a basis for the development of a CT protocol optimisation model.<br /> (© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)

Subjects :: Algorithms
Analysis of Variance
Child
Contrast Media
Humans
Models, Statistical
Multidetector Computed Tomography standards
Phantoms, Imaging
Radiation Dosage
Radiation, Ionizing
Radiographic Image Interpretation, Computer-Assisted methods
Research Design
Signal-To-Noise Ratio
Tomography Scanners, X-Ray Computed
Multidetector Computed Tomography methods
Pediatrics methods

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