Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family.

Authors :: Yoo HJ
Woo RS
Cho SC
Kim BN
Kim JW
Shin MS
Park TW
Son JW
Chung US
Park S
Park M
Kim SA
Source :: Psychiatry research [Psychiatry Res] 2015 Jun 30; Vol. 227 (2-3), pp. 366-8. Date of Electronic Publication: 2015 Mar 23.
Publication Year :: 2015
Abstract: To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.<br /> (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)

Subjects :: Child
Child Development Disorders, Pervasive ethnology
Ethnicity genetics
Female
Genetic Testing
Genome-Wide Association Study
Humans
Male
Phenotype
Polymorphism, Genetic
Polymorphism, Single Nucleotide
Republic of Korea
Schizophrenia ethnology
Asian People genetics
Child Development Disorders, Pervasive genetics
Neuregulin-1 genetics
Schizophrenia genetics

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