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A new aliphatic alcohol and cytotoxic chemical constituents from Acorus gramineus rhizomes.
- Source :
-
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2015; Vol. 79 (9), pp. 1402-5. Date of Electronic Publication: 2015 Apr 15. - Publication Year :
- 2015
-
Abstract
- A new aliphatic alcohol, (2R,6R)-oct-7-ene-2,6-diol (1), and seven other known compounds (2-8) were isolated from Acorus gramineus rhizomes. The structure of 1 was elucidated by a combination of extensive spectroscopic analyses, including 2D NMR, HR-MS, and the modified Mosher's method. Compounds 3-8 displayed consistent antiproliferative activities against the cell lines tested with IC50 values ranging from 7 to 48 μm.
Details
- Language :
- English
- ISSN :
- 1347-6947
- Volume :
- 79
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Bioscience, biotechnology, and biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 25874728
- Full Text :
- https://doi.org/10.1080/09168451.2015.1031079