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Unusual clear cell, lymphoplasmacyte-rich, dural-based tumor with divergent differentiation: a tricky case mimicking a meningioma.

Authors :
Miracco C
Toscano M
Butorano MA
Baldino G
Tacchini D
Barone A
Cerase A
Source :
Human pathology [Hum Pathol] 2015 Jul; Vol. 46 (7), pp. 1050-6. Date of Electronic Publication: 2015 Mar 25.
Publication Year :
2015

Abstract

We describe an unusual case of a recurrent dural neoplasm, previously diagnosed as meningioma. Histopathologically, the tumor is characterized by aggregates of divergently differentiated clear cells embedded in an abundant lymphoplasmacyte-rich stroma, mimicking a lymphoplasmacyte-rich meningioma. This study focuses on the histologic and immunohistochemical characterization of a unique dural-based tumor and provides useful guidelines for differentiating meningioma from other uncommon dural-based neoplasms. We propose that this recurrent dural neoplasm is a distinctive entity and, therefore, enlarges the spectrum of dural-based neoplasms that enter the differential diagnosis with meningiomas. Awareness of this tumor entity could prove useful for appropriate patient management.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1532-8392
Volume :
46
Issue :
7
Database :
MEDLINE
Journal :
Human pathology
Publication Type :
Academic Journal
Accession number :
25912756
Full Text :
https://doi.org/10.1016/j.humpath.2015.03.006