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Unusual clear cell, lymphoplasmacyte-rich, dural-based tumor with divergent differentiation: a tricky case mimicking a meningioma.
- Source :
-
Human pathology [Hum Pathol] 2015 Jul; Vol. 46 (7), pp. 1050-6. Date of Electronic Publication: 2015 Mar 25. - Publication Year :
- 2015
-
Abstract
- We describe an unusual case of a recurrent dural neoplasm, previously diagnosed as meningioma. Histopathologically, the tumor is characterized by aggregates of divergently differentiated clear cells embedded in an abundant lymphoplasmacyte-rich stroma, mimicking a lymphoplasmacyte-rich meningioma. This study focuses on the histologic and immunohistochemical characterization of a unique dural-based tumor and provides useful guidelines for differentiating meningioma from other uncommon dural-based neoplasms. We propose that this recurrent dural neoplasm is a distinctive entity and, therefore, enlarges the spectrum of dural-based neoplasms that enter the differential diagnosis with meningiomas. Awareness of this tumor entity could prove useful for appropriate patient management.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Subjects :
- Diagnosis, Differential
Dura Mater chemistry
Dura Mater surgery
Female
Humans
Immunohistochemistry
Magnetic Resonance Imaging
Meningeal Neoplasms chemistry
Meningeal Neoplasms surgery
Middle Aged
Neoplasm Recurrence, Local
Predictive Value of Tests
Biomarkers, Tumor analysis
Cell Differentiation
Dura Mater pathology
Meningeal Neoplasms pathology
Meningioma pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8392
- Volume :
- 46
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Human pathology
- Publication Type :
- Academic Journal
- Accession number :
- 25912756
- Full Text :
- https://doi.org/10.1016/j.humpath.2015.03.006